Re: essence fragmentation
If you are talking about Soul Retrieval, I would imagine that it is possible there could be added complications and difficulties and things that just make it harder than usual - but not impossible.
Re: essence fragmentation
from what i've been reading lately, it seems that the soul fragments, which retreated during trauma, often go to a place that is far more "friendly" than real-life has been.
often the shaman doing the retrieval finds that the soul fragment refuses to come back, and so has to be persuaded, and even tricked, into coming back.
even when it has returned, it needs to be nurtured by the individual it was once a part of. retaining the memory of the original trauma, it may be unsure of it's safety, back in the real world.